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Michael Phelps picked up his 19th gold medal on a second night of world records in the Olympic pool, with Katie Ledecky cruising to women’s 400 meters freestyle victory and Britain’s Adam Peaty running away with the men’s 100 breaststroke. (RIO 2016 FULL COVERAGE)Sweden’s Sarah Sjostrom extended Saturday’s record spree in winning the 100 meters butterfly, and Peaty and Ledecky followed suit in the next two finals before the U.S. men’s team, with Phelps swimming second, took the 4×100 freestyle relay.Six swimming world records have now fallen in two days of competition, and the United States moved level with Australia on two gold medals each.Phelps, the most decorated Olympian of all time, now has 19 golds, two silvers and two bronzes. For his relay team mates Caeleb Dressel and Ryan Held, it was their first Olympic medal.London Olympics 100 freestyle champion Nathan Adrian swam the final leg for the Americans, touching first ahead of France and Australia.”On the block I thought my heart was going to explode, I was so hyped, so excited,” said Phelps, competing in his fifth Olympics.Ledecky, the rising U.S. swimming sensation, shaved 1.91 seconds off her own world record on the way to the 400m gold, the first stage of a rare treble she hopes to complete along with the 200m and 800m.”It’s pure happiness,” the 19-year-old told reporters.
Chris Froome believes that the vitriol directed at Team Sky during the Tour de France spurred them on. The four-time winner, who has been booed during almost every stage, spat at and had an unidentified liquid poured on him, said the team had bonded over the incidents.“It brought us together,” he said. “We bonded faster this year. It feels as if it was us against the world. It was amazing how the team pulled through especially when off the bike it’s been more difficult.”Froome, who finished second in Saturday’s 31km time trial from Saint-Pée-sur-Nivelle to Espelette, also paid tribute to Geraint Thomas, who will finish with the yellow jersey in Paris on Sunday.“I didn’t need to give him much advice,” he said. “He was in yellow last year, he’s seen me in these situations. We were always very open and honest with each other. It was clear once we hit the Alps that Geraint was in better physical condition so it was pretty simple.” Share on WhatsApp “This was a similar type of day to when he has ridden in big Olympic finals,” he said. “You have to keep focusing on the process rather than wonder about whether it rains, whether he crashes, or what your rivals are going to do.“He was nervous. There is always going to be performance anxiety at this level but the way he handled it was the key.”Tom Dumoulin, who won the time trial by one second from Froome, paid tribute to Thomas, who he said was the strongest man in the race. “He was in the shape of his life. He never made any mistakes, he was never put into any trouble in the mountains and I only have big respect for him.” Reuse this content Cycling Share on Facebook Share on Pinterest Dave Brailsford praised Froome for his behaviour towards Thomas. “Chris came here to win,” said the Team Sky principal. “He didn’t come here to get on the podium. There was a moment he realised he wasn’t going to win and it would have been understandable for him to have a little moment. But the first thing he did was to get on the front and help Geraint.“That’s rare. And it sums him up. To have the class to do that when he was most challenged, you can see into the heart and the soul of that guy and you know what he is about. Geraint will be a legend in Britain and Wales, but Chris is a titan.”Brailsford said Thomas had been nervous before the individual time trial, especially given the difficulties of riding on skiddy roads, but that Thomas’s experience of winning Olympic gold had helped keep the butterflies away. Share on Messenger Sign up to The Recap, our weekly email of editors’ picks. Share on LinkedIn ‘It should be enough’: Geraint Thomas confident of Tour de France triumph news The Observer Geraint Thomas Team Ineos Since you’re here… Tour de France Chris Froome Support The Guardian Share via Email Topics Tour de France 2018 Read more … we have a small favour to ask. More people, like you, are reading and supporting the Guardian’s independent, investigative journalism than ever before. And unlike many news organisations, we made the choice to keep our reporting open for all, regardless of where they live or what they can afford to pay.The Guardian will engage with the most critical issues of our time – from the escalating climate catastrophe to widespread inequality to the influence of big tech on our lives. At a time when factual information is a necessity, we believe that each of us, around the world, deserves access to accurate reporting with integrity at its heart.Our editorial independence means we set our own agenda and voice our own opinions. Guardian journalism is free from commercial and political bias and not influenced by billionaire owners or shareholders. This means we can give a voice to those less heard, explore where others turn away, and rigorously challenge those in power.We hope you will consider supporting us today. We need your support to keep delivering quality journalism that’s open and independent. Every reader contribution, however big or small, is so valuable. Support The Guardian from as little as $1 – and it only takes a minute. Thank you. Share on Twitter
11 Pedro Share on WhatsApp 10 Aguero Chelsea’s Maurizio Sarri: Kepa substitution row a ‘misunderstanding’ – video Manchester City Read more Possession Kepa Arrizabalaga refused to leave the pitch after his manager attempted to substitute him. Photograph: Tom Jenkins/The Guardian 13 Caballero (s 46′) Ederson, City’s goalkeeper, saved from Jorginho with the first kick of the shootout and David Luiz hitting the post with Chelsea’s fourth effort was the decisive miss. César Azpilicueta and Emerson had beaten Ederson and Eden Hazard did so with the most outrageous chip. Yet the occasion will be remembered for the refusal of Chelsea’s goalkeeper to leave the pitch, the public show of rage from his manager and the unmistakable feeling that we were witnessing something unprecedented in a Wembley final.Sarri was so incensed he stormed down the tunnel and, briefly, it was not entirely clear that he would even return. He thought better of that one – but it needed Antonio Rüdiger to hold him back from getting to the Spaniard before the game went to penalties. Share on Messenger Pinterest 20 Hudson-Odoi Sarri and Kepa try to play down substitution ‘misunderstanding’ Hazard had looked the most threatening player and Chelsea appeared to have learned from their Manchester ordeal. They were quick to the ball, they chased down their opponents and played with a collective understanding that, before anything else, they had to find a way to disrupt City’s rhythm. The Fiver: sign up and get our daily football email. 7 Sterling 19 Sane Topics 2 Rudiger Quick guide Follow Guardian sport on social media Share on Twitter Share on LinkedIn Goal attempts Play Video 47 Foden 21 Silva Facebook Lineups 9 Higuain 4 7 7 Chelsea Off target 11 Man City 0 Chelsea On target 2 Man City 49 Muric 17 De Bruyne Fouls Was this helpful? Share on Pinterest Chelsea 8 Gundogan 28 Azpilicueta Share via Email 7 21 33 Emerson Palmieri 2 Walker 12 Loftus-Cheek Thank you for your feedback. 2:17 Substitutes Twitter: follow us at @guardian_sportFacebook: like our football and sport pagesInstagram: our favourite photos, films and storiesYouTube: subscribe to our football and sport channels Substitutes 20 Bernardo Silva 18 Giroud Show (s 89′) Read more Hide 17 Kovacic Once they had managed that, Chelsea started to look increasingly dangerous in the second half, whereas their only threatening moment in the opening 45 minutes came when N’Golo Kanté set off after a long ball through the middle and looked as though he might get a clear run behind the defence.As often happens with this referee, Moss was some way behind play when Oleksandr Zinchenko cut across Kanté and the Chelsea player went down. A free-kick in that position would have meant a red card and that was certainly what the end of the stadium wearing the darker shade of blue wanted. Instead, Moss waved on play and, more by luck than anything else, that was probably fair given that Kanté had controlled the ball on his hand as he ran between Aymeric Laporte and Zinchenko.Laporte went off at half-time and when Fernandinho was injured later on that meant City, with all three substitutes used, had to wait until extra time before they could bring on a fourth, Danilo, in place of the Brazilian.Ultimately, though, the game will be remembered for the substitution that never was and, knowing what we do about Roman Abramovich, a farce that could have serious repercussions for the man who, for now, holds the title of Chelsea manager. (s 79′) 22 Willian 27 Christensen Photograph: Chesnot/Getty Images Europe 5 Jorginho 7 Kante 3 Danilo MNC CHE 8 Barkley 25 Fernandinho 60 40 Share on Facebook 30 Luiz To his credit, the goalkeeper did manage to keep out Leroy Sané’s penalty. Not that it mattered, ultimately, when he also let one from Sergio Agüero go beneath his body, preceded by some failed Grobbelaar‑esque silliness to put off the scorer, and could not keep out the ones from Ilkay Gündogan and Bernardo Silva either. When the final kick was delivered, who would have wanted to be in the boots of Kepa Arrizabalaga? Raheem Sterling was setting off on his victory run, the trophy was back in Manchester City’s possession and Pep Guardiola had another piece of silverware for his collection. Yet that told only part of the story bearing in mind the incredible scenes involving Maurizio Sarri, his headstrong goalkeeper and the public show of disobedience that could conceivably accelerate the process of Chelsea looking for another manager.It was a remarkable finale and an unorthodox one, too, bearing in mind Sarri’s failed attempts to substitute Arrizabalaga just before the game headed into the penalty shootout. Arrizabalaga had gone down twice with cramp in extra time and Sarri wanted to bring on Willy Caballero, a goalkeeper who had saved three penalties for City when they won this competition in 2016 with a shootout victory against Liverpool. 14 Laporte (s 91′) 1 Arrizabalaga Match stats match reports 10 Hazard (s 95′) (s 86′) Corners Man City 26 Mahrez Kepa’s shootout mutiny emblematic of Sarri’s sinking ship at Chelsea Carabao Cup Chelsea 30 Otamendi 31 Ederson MNC60CHE40% Arrizabalaga clearly had other ideas, signalling that he was fit, making it absolutely clear he had no intention of going off, then holding his ground and leaving Sarri close to the point of spontaneous combustion on the touchline. Caballero, the penalty specialist, was stripped from his tracksuit, ready to come on, but Arrizabalaga did not care. It was a staring contest – and Arrizabalaga’s refusal to blink meant he was always going to be the hero or villain in the shootout. 4 Kompany 35 Zinchenko (s 79′) Twitter To describe Sarri as livid would be an understatement. Justifiably, too, because it would be rare at any level to see a manager being disobeyed this way. For it to happen in a final, with his job potentially on line, was a calamity. The referee, Jon Moss, should have been firmer and told Arrizabalaga his number had flashed up on the electronic board and, frankly, that he needed to get off the pitch. Worse for Sarri, not enough Chelsea players backed up their manager. David Luiz tried to talk some sense into Arrizabalaga with no success. But where was Azpilicueta, the captain? Or the other senior players?Not that City will care about those kind of details after winning this trophy for the fourth time in six seasons. It was their sixth victory overall and that means there is only Liverpool, with eight, who have been more successful in this competition. Pep Guardiola continues to insist a quadruple will be impossible, but it will not be for the lack of trying and, judging by the scenes at the end, they will have a lot of fun trying to find out.For now, it should be enough that they have secured the season’s first silverware with a performance that was below their best – and certainly a long way short of the six-goal rampage in Manchester a fortnight ago when they inflicted Chelsea’s heaviest defeat since 1991.The last time they played one another, Chelsea were four goals down after 24 minutes. This time City managed one shot on target throughout the first 90 minutes. There was even the strange phenomenon of Kevin De Bruyne misplacing several passes before being substituted. David Silva was also replaced. Reuse this content
MIAMI, FL – DECEMBER 29: Head coach Lincoln Riley of the Oklahoma Sooners looks on prior to their College Football Playoff Semifinal against the Alabama Crimson Tide at the Capital One Orange Bowl at Hard Rock Stadium on December 29, 2018 in Miami, Florida. (Photo by Michael Reaves/Getty Images)Oklahoma head coach Lincoln Riley has been mentioned as a possible candidate for an NFL job, with the Cleveland Browns being named as a potential destination.Riley, though, doesn’t appear to be interested in leaving Oklahoma anytime soon.The Sooners’ head coach said following his team’s loss to No. 1 Alabama that he doesn’t view the NFL as a “step up.”“I don’t see that as a step up, not in this profession. It’s not a burning desire of mine by any stretch right now. Not even close. It doesn’t even compare to my burning desire to win a national championship here,” Riley told reporters.Riley understands his name will come up for NFL jobs.”I don’t see that as a step up, not in this profession. It’s not a burning desire of mine by any stretch right now. Not even close. It doesn’t even compare to my burning desire to win a national championship here.”#Sooners— Eric Bailey (@EricBaileyTW) December 30, 2018Riley, 35, is in his second season as Oklahoma’s head coach.The Sooners have gone 24-4 in Riley’s two seasons as head coach, making the College Football Playoff both years.Oklahoma will likely be a championship contender in the Big 12 again next season, though the Sooners will need to replace Kyler Murray.Georgia five-star freshman quarterback Justin Fields is reportedly considering Oklahoma as a transfer option.
zoom US-based private equity firm Advent International has agreed to acquire a majority ownership interest in maritime services provider V.Group from OMERS Private Equity (OPE). OPE will reinvest in V.Group, “working with Advent and the management team to support the continued growth and development of the business” and V.Group’s management team will retain a minority stake in the company, Advent said.The value of the transaction was not disclosed.“We have enjoyed great support and solid growth under OPE’s ownership, and our company has continued to strengthen its position in the market through our recent acquisitions of Bibby Ship Management and Selandia Holdings,” Clive Richardson, CEO of V.Group, said.V.Group, which specializes in the technical management of maritime assets outsourced by ship owners, manages over 1,000 vessels across the commercial shipping, cruise, energy and defense sectors.Last month, V.Group acquired Mumbai-based maritime services provider Selandia Holdings and its subsidiaries, comprising the Selandia Ship Management Group, as part of its plans to expand to Asia.Advent said that, following its investment, V.Group’s growth strategy will remain focused on further geographical expansion and deepening its range of services organically and through complementary acquisitions.
zoom Floating energy solutions provider Höegh LNG has signed a long-term Floating Storage Regasification Unit (FSRU) contract with Global Energy Infrastructure Limited (GEIL) for the liquefied natural gas (LNG) import project in Port Qasim near Karachi, Pakistan. The charter is for a period of 20 years with two five year extension options for charterer and is expected to generate an average annual EBITDA of around USD 36 million. The contract is subject to both parties’ board approval.The project is the first private LNG import terminal in Pakistan and will be located at the LNG zone in Port Qasim. Back in September, GEIL signed a long-term LNG supply agreement with Qatargas.“In addition to this major milestone, we have already executed a 1.3 MTPA for 20 years LNG supply with Qatargas. Furthermore, we are near signing an additional 3 MPTA of LNG supply with two major LNG producers as well as nearing to sign the EPC contract for the facility,” GEIL’s Group CEO Ahmet Caliskan said.The construction of the terminal is planned to commence early 2017 and expected start-up is second quarter of 2018.The FSRU will be provided from Höegh LNG’s portfolio of FSRUs, including units under construction, the planned conversion FSRU or from new FSRU’s on order.”With this contract we have full contract coverage for our FSRU fleet of 9 units on the water and under construction,” Höegh LNG’s President and Chief Executive Officer, Sveinung J. S. Støhle, said.
FORT ST. JOHN, B.C. – The RCMP want to remind drivers to slow down for the current winter driving conditions.The RCMP shared, with snow clearing taking place on some of the streets and avenues, conditions can improve immensely but they can also become more slippery, depending on a variety of factors. Recently, while the RCMP attended a motor vehicle collision between two vehicles at a high use intersection, another collision occurred between two more vehicles.Road conditions may be contributing factors but drivers can still be ticketed for Speed Relative to Conditions for a fine of $167.00 (Sec. 144(1)(c) Motor Vehicle Act) as they did not slow down enough to maintain control as they approached the intersection. “The known or posted speed signs don’t change on our roads,” said Cst Neustaeter, “but conditions do.”A person must not drive at a speed that is excessive relative to the road, traffic, visibility or weather conditions, shared the RCMP.The RCMP are reminding drivers to be aware of where pedestrians may interact with traffic such as crosswalks and when pedestrians enter the roadway to get into their vehicles. The road can be uneven and slippery for pedestrians. Drivers who slow down have more time to react if the pedestrian slips or falls.Drivers are responsible for driving at a reasonable speed that protects them from sliding through intersections, causing a collision with another vehicle or person. These collisions are preventable when drivers slow down and drive relative to conditions shared the RCMP.
In a message, Mr. Annan said, “outer space was once seen as a potential source of conflicts. But happily, it has become a source of cooperation. Many scientific achievements in outer space were possible because scientists from different countries worked together. ” Stressing that the benefits of space exploration should not be the “privilege of a limited few,” Mr. Annan said that advances in space science and technology could help developing countries deal with a range of issues — from natural disasters to modern communications. “Space science and technology have a great potential for enriching the lives of people around the world,” Mr. Annan said. Earth observation satellites could provide essential data to give early warnings for extreme weather phenomena, he noted, and satellite communications could help close the “digital divide.” “We must all work to ensure that the possibilities offered by technology, both in outer space and here on earth, are used to foster tolerance, trust and shared values,” he said. “They must not be allowed to become instruments of discord or division.”
Analyst says Target pull out not surprising by News Staff Posted Jan 16, 2015 7:40 am MDT A senior instructor at the University of Calgary’s Haskayne School of Business says Target’s decision to pull up stakes in Canada comes as no big surprise, given their steep losses.However, the timing is.The U.S retailer announced Thursday it was closing all 133 stores across the country, throwing more than 17,000 people out of work.Lynne Ricker with the Haskayne School of Business tells City News, she is surprised they gave up so quickly, after just two years.“Everybody can see their original mistake not having enough products on the shelf when you open. Customer expectations were pretty high; Canadians were pretty familiar with Target. They knew what to expect when they went into the stores, Target didn’t deliver that,” she said.Ricker says it’s hard to recover from a bad first impression. AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email
Former Ohio State quarterback Terrelle Pryor was declared eligible for the NFL supplemental draft, now scheduled for Monday, in a Thursday announcement by the NFL.Pryor has also been assessed a punishment by NFL commissioner Roger Goodell and, if drafted, will be suspended from games and practices through Week 5 of the NFL season, according to an NFL press release.After begin drafted and signed to a contract, Pryor would be allowed to fully participate in the remainder of preseason, though.David Cornwell, Pryor’s attorney, did not immediately respond to The Lantern’s request for a comment.After initially agreeing to a suspension for the first five games of OSU’s upcoming season, Pryor departed the university on June 7 to pursue a professional football career. His departure came just days after former head coach Jim Tressel was forced to resign from his position. Pryor was then declared ineligible for intercollegiate athletics in a July 26 letter from OSU athletic director Gene Smith.The NFL press release, which confirmed that all 32 NFL clubs have been informed of Pryor’s draft eligibility, said:“NFL clubs were informed that Pryor made decisions that undermine the integrity of the eligibility rules for the NFL Draft. Those actions included failing to cooperate with the NCAA and hiring an agent in violation of NCAA rules. This resulted in Ohio State declaring him ineligible to continue playing college football. Pryor then applied to enter the NFL after regular draft. Pryor had accepted at the end of the 2010 college football season a suspension for the first five games of the 2011 season for violating NCAA rules.“In his decision allowing Pryor to enter the Supplemental Draft, (Goodell) determined that Pryor will be ineligible to practice prior to or play in the first five games of the NFL regular season after he signs. Pryor may be selected in the Supplemental Draft, negotiate and sign a contract with an NFL club, and fully participate in the remainder of the preseason.”From his Twitter account, @TerrellePryor, Pryor tweeted at approximately 9:30 a.m.: “God bless and thanks for support! Time to have a little fun!!”Pryor joins five other players in Monday’s draft, which is scheduled to begin at 1 p.m.
David Gauke, the Justice Secretary, has demanded a list of all Category A prisoners released directly into the community – rather than spending time in an open jail first. The row over the John Worboys’ parole fiasco has intensified after officials admitted 63 violent criminals – including murderers and rapists – were similarly cleared for release last year from high-security jails straight on to Britain’s streets. Ministers were last night seeking assurances that the freed prisoners had been subject to proper scrutiny by the Parole Board. The Parole Board had still to hand over the list on Thursday evening but hit back, claiming the public is often safer if offenders are placed in the community…
WARNING Please note, we have found blue punishers in the confiscation box. They are potentially lethal. This is what we have been warning about #BeSafe pic.twitter.com/iyMCRQtg3l— Parkalife (@Parklifefest) June 9, 2018 Dangerous drugs which are mis-sold as MDMA but cause psychosis and keep young users awake for up to three days are being sold at Parklife festival, narcotics experts have warned.”Fake MDMA” drug N-Ethyl-Pentylone, which is three times as strong as the drug it mimics, has been found at the Manchester music festival.It was first detected in the US in 2016, and then it spread to Australia in 2017, where users had to be sedated after the effects of the narcotic substance took hold. It has also been linked to deaths and mass casualties at music festivals around the world.The drug is so dangerous because it can be easily mistaken for MDMA, drug testers from The Loop said.However, it does not give the same high as MDMA, which leads some to accidentally overdose, and it is three times as strong.Although users feel a short, semi-euphoric high when they first ingest the drug, this gives way to three days of sleepless nights, paranoia and psychosis. We tested a gram of n-ethyl pentylone @Parklifefest yesterday – looks & smells same as MDMA crystal. Relieved this user didn’t take it. Take care & seek medical attention if unwell. #JustSayKnow #TimeToTest pic.twitter.com/mWVkPHvhPQ— The Loop (@WeAreTheLoopUK) June 10, 2018 The popular dance festival was cancelled as a “safety precaution” after the death of 18-year-old care worker Georgia Jones and Tommy Cowan, a 20-year-old man.Before their deaths, organisers said they were aware of “dangerous high strength or bad batch” of drugs on site.The Loop also found the dangerous super-strong pills on site at Mutiny.Parklife alluded to this, tweeting: “We all saw the sad news last weekend. There are batches of very bad pills out there at the moment. Please act responsibly and look after each other.”A spokeswoman for Greater Manchester Police confirmed 28 people had been arrested at the Heaton Park festival on Saturday, 23 of them on suspicion of committing drugs crimes. Parklife Festival organisers warned attendees to take special care after super-strong ecstasy tablets were found in confiscation boxes.They wrote: “WARNING Please note, we have found blue punishers in the confiscation box. They are potentially lethal. This is what we have been warning about.”The same “bad pills” were linked to two deaths and 12 hospitalisations at Mutiny festival in Portsmouth two weeks ago. The Loop found a gram of the substance at Parklife festival, leading to worries that more was in circulation, being mis-sold as MDMA.When the drug hit Australia in 2017, Dr David Caldicott, an expert in emergency medicine, told The New Daily: “It has been clearly responsible for the deaths of people overseas, and a rather unfortunate phenomenon known as ‘mass casualty overdoses’, where 10-20 people drop simultaneously. So, it’s of great concern to the music festival environment.” Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily Front Page newsletter and new audio briefings.
← Previous Story VIDEO: VELUX EHF CL (Round 4) BEST 7! Next Story → Zlatko Horvat broke right hand against La Rioja Macedonian Handball FederationRisto Magdincev Macedonian Handball Federation sacked the head-coach of the Women’s NT Risto Magdincev due bad results at the start of the qualifications for the World Championship 2015 in Denmark. Macedonia has suffered two surprising defeats against Italy (20:23 and 22:27) at the start of the Group stage and stayed almost without chances to qualify for the knock-out stage.Iceland is the third NT in the group with Italy and Macedonia.Management Board of the Macedonian Handball Federation will decide about Magdincev’s successor on the next meeting.
1998–20042004–20072007–20092009–20132013–2018Chambéry Savoie HandballVfL GummersbachChambéry Savoie HandballTHW KielParis Handball Legendary French player Daniel Narcisse announced retirement at the end of the season. The 38-years old left back won all major titles in world of handball, but still want to finish professional career in the big style – with winning VELUX EHF Champions League with Paris Saint Germain.I am quite a shy person, I tend not to show my emotions,” he says. “Talking about the team or other players has never been a problem for me, but when you are in the middle of the process, it is much harder. I had trouble finding the right words and it wasn’t an easy moment.”Daniele will retire with nine gold medals from major events like World, European or Olympic tournaments.Narcisse’s career: ← Previous Story Spaniards had no mercy for African champions Next Story → Draw for Men’s EHF EURO 2020 qual in Trondheim Daniele NarcissePSG Handball
Toxoplasma gondii, le parasite qui rend les souris intrépides face aux chatsSi les chats savent se faire aimer des humains, ils semblent être aussi capables d’amadouer les souris. Pas grâce à leur charme irrésistible, mais plutôt à cause du parasite Toxoplasma Gondii. Ce dernier transformerait les souris en d’intrépides Jerry, loin d’être effrayés par leurs ennemis félidés. Mais à la différence du héros animé, les petits mammifères deviennent ensuite des proies idéales. Des souris sans peur et un parasite aux anges, voilà le résultat du trio chat-souris-toxoplasmose. C’est ce qu’a découvert la scientifique Wendy Ingram de l’Université de Californie et ses collègues après avoir étudié pendant plusieurs années le parasite et ses effets sur les rongeurs. Elle révèle ainsi que les souris infectées par le parasite de la toxoplasmose perde leur peur des chats, plus particulièrement de l’odeur de leur urine. Un changement bénéfique pour les matous qui voient leurs proies venir directement à eux, mais également pour le parasite. En effet, ce dernier accède facilement à l’intestin des félins, le seul endroit où il peut se reproduire et perpétuer le cycle de l’infection.Un effet permanent sur les sourisAu cours de leurs travaux, les chercheurs se sont également aperçus que l’effet est particulièrement rapide, et surtout, permanent. En trois semaines, les souris perdent complètement leur peur de l’urine de chat. Et même lorsque l’infection est soignée, les rongeurs conservent les symptômes. “Une sorte de changement comportemental à long-terme se produit, même si les parasites ont été totalement retirés de l’organisme et du cerveau de la souris. Pour le moment, nous n’en connaissons pas les mécanismes précis”, explique Wendy Ingram, repris par Science Daily. Selon elle, le parasite pourrait en fait endommager le centre de l’odorat dans le cerveau des souris. Il pourrait également altérer les neurones responsables de la mémoire et de l’apprentissage, faisant oublier aux rongeurs leurs instincts primaires. Assistée par Michael Eisen et Ellen Robey, professeurs en biologie moléculaire, Wendy Ingram a mis trois ans pour découvrir les effets du parasite de la toxoplasmose sur les souris. Elle a effectué des tests sur des rongeurs afin de déterminer leur réaction face à l’urine de chat, qu’ils craignent, et à l’urine de lapin, qu’ils ignorent. Ceci lui a permis de déterminer que les trois souches les plus communes de Toxoplasma gondii rendent les souris insensibles à la peur des chats pour au moins quatre mois. Grâce à une souche modifiée du parasite, qui ne forme pas de kystes dans le cerveau, elle a démontré que les effets perduraient au-delà de quatre mois, même après évacuation de l’infection.Un parasite intelligentActuellement, les chercheurs tentent de mettre à jour les réponses du système immunitaire des souris à l’infection. En déterminant l’action du système immunitaire sur le parasite, Wendy Ingram pourra ainsi déterminer si la réponse à l’infection est responsable de ces symptômes. Selon Michael Eisen, “ces découvertes permettraient de réfuter les modèles dans lesquels les changements de comportements sont le résultat direct de l’action physique des parasites sur une partie spécifique du cerveau”, reprend Science 2.0. “Ce parasite est capable de comprendre les cerveaux des mammifères afin de faciliter sa transmission au cours d’un cycle de vie compliqué, c’est absolument fascinant”, ajoute Wendy Ingram. Un risque pour l’être humainÀ lire aussiMaladie de Charcot : symptômes, causes, traitement, où en est on ?Mais, les souris ne sont pas les seules à être menacées par ce parasite protozoaire. Si le Toxoplasma Gondii affecte le comportement des souris et des rats, il est également dangereux pour l’Homme. Wendy Ingram estime ainsi qu’environ un tiers de la population mondiale est infectée, mais que le système immunitaire empêche leur action. En revanche, l’infection est particulièrement mortelle pour les fœtus des femmes enceintes ou bien les personnes immuno-déficientes. Certaines études préliminaires suggèrent même que l’infection pourrait être liée à la schizophrénie ou à des comportements suicidaires. Les chats, la viande pas assez cuite, le lait non pasteurisé ou encore les fruits et légumes non lavés, sont les principales sources de transmission du parasite chez l’Homme.(Crédits : Wendy Ingram / University of California) Le 24 septembre 2013 à 09:46 • Emmanuel Perrin
Stay on target At first glance, Instrument 1 looks like a controller for some off-brand Guitar Hero clone. For their first product, the makers at music technology company Artiphon said they did look at those peripherals for inspiration. But this smart instrument, the “most funded musical gadget in Kickstarter history,” is actually about democratizing the joys of composing music, not just mechanically imitating it.After spending some time jamming with Instrument 1 at art/tech incubator New Inc., all I can say is it makes me want to get back into music.Instrument 1 is a MIDI controller, a tool for generating the standard digital music file. But whereas most MIDI controllers are keyboards hooked up to inscrutable boxes, Instrument 1 is shaped like a purposefully vague string instrument.Typing notes into software can’t capture the totality of writing and performing music. The physical act of hitting a drum or plucking a string or moving yours hands up and down piano keys, on stage or in a tour bus, is crucial to the experience. Instrument 1 wants to replicate that. Pressure sensitive buttons let you strum, press frets, or even hold the device up on your shoulder like a violin. And if you lay it on a surface, the neck acts as a piano/drum kit.Remember Wii Music? That game got a ton of flak after its infamous showing at Nintendo’s 2008 E3 Conference (Ravi Drums?) and the end product was pretty basic. But I also appreciated how the game approached music from a looser and more expressive angle, an opposite but equally valid philosophy compared to Guitar Hero’s strict focus on technical rhythmic precision.Ultimately, both game’s methods were incomplete, because they were games. But improvising on Instrument 1 felt like joining those concepts and taking them to their logical conclusion as a full-fledged tangible creative music tool. It’s like air guitar but real. Forget recorders, let kids play this in schools.Instrument 1 just feels so good to use. You’ll never forget you’re strumming buttons instead of real string, but the fact that you’re strumming, moving up octaves or using a capo, is still incredibly dope. And while the neck’s buttons aren’t laid out exactly like a piano, it surprised me how quickly my finger muscle memory returned and I was able to play a section of the theme from The Legend of Zelda: Breath of the Wild. Of course, I plugged in my headphones as I didn’t want co-creator Jacob Gordon to hear how rusty I was.Interacting with a MIDI controller in this more realistic way is Instrument 1’s hook, so if you’re serious about using it to its full potential the next step is to connect it to a digital audio workstation like GarageBand on Mac or FL Studio on PC. For this demo, I used Artiphon’s own Instrument 1 iOS app on an iPad (the Android version isn’t ready). I could easily lay down tracks, customize the button layout, lock into a certain harmony, activate tools like the arpeggiator for easy loops, or switch to different instruments.Any good MIDI controller lets composers play not just virtual pianos and guitars but virtual trumpets and xylophones and weird vaporwave synth sounds. But with Instrument 1 you can mix and match those sounds with the different ways you physically play the device. Want to play a violin that makes saxophone noises? You can. A button on the device lets you quickly swap between your favorite sound presets.When I was younger I played the trumpet, and I got pretty good at it. Around middle school I decided I’d rather write music than perform it and got a MIDI keyboard and software. But eventually I realized that to really get serious about music I would have to commit to it as an artistic pursuit, and I didn’t because I was more invested in writing. People only have so much time. I think that was the right choice, but I still feel bad for abandoning that interest.Artiphon is betting there are a lot of other folks who feel the same way, and the company wants Instrument 1 to be a bridge for casual folks to discover (or rediscover) the joys of making sweet music. Imagining how much I would have used this thing as a kid, or even now in the alternate universe where I am a music professional, I think they’re onto something. No wonder they’re showing it off at museums.Instrument 1 is available now for $399. You can learn more on Artiphon’s site. 11 Ways the Wu-Tang Clan Shaped Geek CultureSpotify’s Rise to Power Dramatized in TV Mini-Series
Google+ Whats On Deck For March: Celtics, Bruins Stretch Runs Ric Flair Rushed to Hospital After Medical Emergency Austen Allen b d his legend never will August 14, 2017 at 4:10 pm Ric Flair Wrestling legend Harley Race still hospitalized, team starts up a fundraiser to cover expenses Comments are closed. WhatsApp Now Playing Up Next Facebook Now Playing Up Next Videos Articles August 14, 2017 at 3:18 pm crg beauregard Pinterest Now Playing Up Next August 14, 2017 at 10:19 pm Now Playing Up Next WWE Hall of Famer “Hacksaw” Jim Duggan hospitalized in Intensive Care Unit Maria Kanellis hospitalized with flu-like symptoms on Tuesday, pregnancy unaffected 3 COMMENTS he’s going to die one day, as will we all. Twitter Now Playing Up Next UPDATE as of 4:50 PM ET: Ric Flair is out of surgery but the situation involving Flair is said to still be extremely serious per a new report by Dave Meltzer. ————————————————————-TMZ.com has a new report up about the current health of WWE Hall of Famer Ric Flair after Flair was hospitalized and placed in an intensive care unit over the weekend for a heart issue. Ric Flair is in a medically induced coma and is preparing for surgery … a rep for the WWE tells TMZ Sports. The 68-year-old wrestling icon was admitted to the hospital early Saturday morning and the situation has gotten more serious. We’re told Flair is set to undergo a procedure momentarily, though we’re not being told what the procedure is … though Pro Wrestling Sheet is reporting that it’s a heart related issue.Flair’s rep had previously asked for thoughts and prayers for the Nature Boy. Story developing … We here at Wrestleview.com send out our well wishes to Flair and his family during this tough time. Recommended videosPowered by AnyClipRic Flair Opens Up About 2017 Health ScareVideo Player is loading.Play VideoPauseUnmuteDuration 0:52/Current Time 0:03Loaded: 100.00%0:03Remaining Time -0:49 FullscreenUp NextThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Replay the list Wrestling Legend Ric Flair to Make Feature Film Acting Debut WWE Hall of Famer Ric Flair Hospitalized Hopefully Nature Boy pulls through Jason Namako RELATED ARTICLESMORE FROM AUTHOR Ric Flair Opens Up About 2017 Health Scare
Vancouver police and other city officials ramped up efforts this fall to clear out homeless encampments on the streets surrounding Share House, the men’s homeless shelter downtown.The area has been a source of ongoing complaints since before ordinances outlawing camping and storage of personal property were put into place more than three years ago. In the past, the blocks have amassed dozens of tents. Earlier this week, the streets around the shelter were occupied by only a handful of homeless people and tents, which were partially collapsed during the day. Through a public records request, The Columbian obtained emails sent between Sept. 12 and Dec. 12 detailing the stepped-up cleanup and enforcement efforts. The emails indicate that the Vancouver Police Department, particularly through its resurrected bicycle officer unit, was trying to more thoroughly enforce the ordinances, which prohibit camping and the storing of property between 6:30 a.m. and 9:30 p.m. Besides Share House, the emails mention cleanups along the Burnt Bridge Creek Greenway and Pearson Field.
My legislation to allow, but not require, cities to extend nightlife hours to 4 am just passed its first committee (Senate Governmental Organization Committee) with bipartisan support. First step toward better nightlife in California. Thank you colleagues! #SB58— Scott Wiener (@Scott_Wiener) March 12, 2019 April 4, 2019 KUSI Newsroom, KUSI Newsroom Categories: California News, Good Morning San Diego, Local San Diego News FacebookTwitter 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSAN DIEGO (KUSI) – The San Diego County Police Chiefs’ and Sheriff’s Association is opposed to extending hours of alcohol sales from 2 a.m. to 4 a.m. in several California cities, with a warning to state lawmakers about the harm it would cause to public health and safety.SB 58 would allow the cities of San Francisco, Oakland, Los Angeles, Sacramento, West Hollywood, Long Beach, Coachella, Cathedral City, Fresno and Palm Springs to extend last call hours from the current 2 a.m. to 4 a.m.The association sent a letter to the California Senate expressing its deep concern and requesting that Senate Bill 58 not become law. Chula Vista Police Chief Roxana Kennedy is vice president of the association.“This is concerning to us in Chula Vista and throughout the South Bay,” Kennedy said. “It will have regional consequences for areas that are within driving distance of the cities where the bars stay open later.”Lead author of SB 28 said after the bill passed a committee that its “first step toward better nightlife in California.” Posted: April 4, 2019 San Diego County law enforcement officials oppose bars staying open later